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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA5
All Species:
13.33
Human Site:
T793
Identified Species:
19.56
UniProt:
O75582
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75582
NP_004746.2
802
89865
T793
A
D
S
N
N
P
E
T
L
F
Q
F
S
D
S
Chimpanzee
Pan troglodytes
XP_001140389
894
100719
T885
A
D
S
N
N
P
E
T
L
F
Q
F
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001088246
1054
117436
T1045
A
D
S
N
N
P
E
T
L
F
Q
F
S
D
S
Dog
Lupus familis
XP_547953
806
90703
P798
H
P
A
D
A
S
T
P
D
A
L
F
Q
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
G761
L
P
A
S
A
A
K
G
T
T
R
R
A
N
G
Rat
Rattus norvegicus
Q63531
735
82865
V727
S
I
L
A
Q
R
R
V
R
K
L
P
S
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
S705
Q
P
T
N
P
P
D
S
N
N
P
E
T
I
F
Chicken
Gallus gallus
Q5F3L1
789
89022
P781
N
P
T
D
S
N
N
P
E
T
I
F
Q
F
S
Frog
Xenopus laevis
P10665
733
82620
V725
S
I
L
A
Q
R
R
V
K
K
L
P
S
T
T
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
M731
S
L
A
Q
R
R
N
M
K
K
L
T
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
R1086
V
V
A
R
I
P
K
R
T
H
R
V
V
R
T
Honey Bee
Apis mellifera
XP_395099
910
102507
E875
E
Q
T
I
N
E
D
E
L
S
V
L
E
S
C
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
Y755
S
N
L
G
M
M
N
Y
R
E
P
N
S
G
T
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
C751
I
P
V
T
T
V
S
C
A
P
R
T
T
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
F463
Y
V
R
P
P
H
S
F
L
H
R
T
T
S
N
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
S669
G
D
E
Q
L
G
D
S
P
S
Q
G
R
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
75
93.1
N.A.
62.8
41
N.A.
82.1
89.4
40
40.5
N.A.
28.5
45.7
46.8
53.3
Protein Similarity:
100
88.5
75.1
95.1
N.A.
76.6
57.9
N.A.
86.1
94.6
57.4
57.3
N.A.
40
62.3
63
66.2
P-Site Identity:
100
100
100
13.3
N.A.
0
6.6
N.A.
13.3
13.3
6.6
6.6
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
100
100
26.6
N.A.
40
20
N.A.
40
33.3
20
20
N.A.
33.3
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
25
13
13
7
0
0
7
7
0
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
0
25
0
13
0
0
19
0
7
0
0
0
0
19
7
% D
% Glu:
7
0
7
0
0
7
19
7
7
7
0
7
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
19
0
32
0
13
7
% F
% Gly:
7
0
0
7
0
7
0
7
0
0
0
7
0
7
7
% G
% His:
7
0
0
0
0
7
0
0
0
13
0
0
0
0
0
% H
% Ile:
7
13
0
7
7
0
0
0
0
0
7
0
0
7
7
% I
% Lys:
0
0
0
0
0
0
13
0
13
19
0
0
0
0
0
% K
% Leu:
7
7
19
0
7
0
0
0
32
0
25
7
0
0
0
% L
% Met:
0
0
0
0
7
7
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
25
25
7
19
0
7
7
0
7
0
7
7
% N
% Pro:
0
32
0
7
13
32
0
13
7
7
13
13
0
0
0
% P
% Gln:
7
7
0
13
13
0
0
0
0
0
25
0
13
0
0
% Q
% Arg:
0
0
7
7
7
19
13
7
13
0
25
7
7
7
0
% R
% Ser:
25
0
19
7
7
7
13
13
0
13
0
0
44
19
32
% S
% Thr:
0
0
19
7
7
0
7
19
13
13
0
19
19
25
25
% T
% Val:
7
13
7
0
0
7
0
13
0
0
7
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _